Simply put, your OS is deliberately blocking NBA 2K14 from starting to protect your computer. We have to trick or force the system to let the game through.
The NBA 2K14 "Failed to Initialize" error is a frustrating collision between classic PC gaming and modern security standards. Because 2K no longer supports this title, the burden falls on you, the player. Nba 2k14 Failed To Initialize Fix Securom
If you reboot your PC, you may need to run sc start secdrv again. Simply put, your OS is deliberately blocking NBA
Sometimes the game "fails to initialize" because it is trying to talk to servers that no longer exist. the burden falls on you