Inside the portable folder, locate the LightroomPortable.ini (or the .reg registration file). Add these lines if available:
If you absolutely must run Lightroom 5.7 portably: lightroom portable 32 bits
Portable apps are forced to run in isolated environments. Because they cannot properly interact with your system registry or GPU drivers, they crash frequently and run incredibly slowly. 🛑 No Adobe Sensei AI or Cloud Sync Inside the portable folder, locate the LightroomPortable